Registry & Research

Pain research helps identify what causes pain, what interventions truly work, and how to improve quality of life for people living with chronic pain. By investing in research, PainUSA can support evidence-based care, influence policy, and ultimately lead way to new therapies and improved outcomes for patients.

You, D. S., Hah, J., Collins, S., Ziadni, M., Domingue, B., Cook, K., Mackey, S. Evaluation of the Preliminary Validity of Misuse of Prescription Pain Medication Items from the Patient-Reported Outcomes Measurement Information System (PROMIS)® Pain Medicine. 11 March 2019. doi.org/10.1093/pm/pnz001. PMID: 30856659

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Barad, M., Sturgeon, J., Fish, S., Dexter, F., Mackey, S., Flood, P. Response to BotulinumtoxinA in a Migraine Cohort with Multiple Comorbidities and Widespread Pain. Regional Anesthesia & Pain Medicine. 2019 Jun;44(6):660-668. doi: 10.1136/rapm-2018-100196. PMID: 31101743

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Smith, D. M., Weitzel, K. W., Elsey, A. R., Langaee, T., Gong, Y., Wake, D. T., … & Nagoshi, Y. (2019). CYP2D6-guided opioid therapy improves pain control in CYP2D6 intermediate and poor metabolizers: a pragmatic clinical trial. Genetics in Medicine, 21(8), 1842-1850.

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Bernstein, C., Gillman, A. G., Zhang, D., Bartman, A. E., Jeong, J. H., & Wasan, A. D. (2020). Identifying Predictors of Recommendations for and Participation in Multimodal Nonpharmacological Treatments for Chronic Pain Using Patient-Reported Outcomes and Electronic Medical Records. Pain medicine (Malden, Mass.), 21(12), 3574–3584. https://doi.org/10.1093/pm/pnaa203

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Gilam, G., Sturgeon, J. A., You, D. S., Wasan, A. D., Darnall, B. D., & Mackey, S. C. (2020). Negative Affect-Related Factors Have the Strongest Association with Prescription Opioid Misuse in a Cross-Sectional Cohort of Patients with Chronic Pain. Pain medicine (Malden, Mass.), 21(2), e127–e138. https://doi.org/10.1093/pm/pnz249

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Hettie, G., Nwaneshiudu, C., Ziadni, M. S., Darnall, B. D., Mackey, S. C., & You, D. S. (2021). Lack of Premeditation Predicts Aberrant Behaviors Related to Prescription Opioids in Patients with Chronic Pain: A Cross-Sectional Study. Substance Use & Misuse, 1-6. PMID: 34369839

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Alter, B. J., Anderson, N. P., Gillman, A. G., Yin, Q., Jeong, J. H., & Wasan, A. D. (2021). Hierarchical clustering by patient-reported pain distribution alone identifies distinct chronic pain subgroups differing by pain intensity, quality, and clinical outcomes. PloS one, 16(8), e0254862. PMID: 34347793

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Barad, M. J., Sturgeon, J. A., Hong, J., Aggarwal, A. K., & Mackey, S. C. (2021). Characterization of chronic overlapping pain conditions in patients with chronic migraine: A CHOIR study. Headache, 61(6), 872–881. https://doi.org/10.1111/head.14129

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