Registry & Research

Pain research helps identify what causes pain, what interventions truly work, and how to improve quality of life for people living with chronic pain. By investing in research, PainUSA can support evidence-based care, influence policy, and ultimately lead way to new therapies and improved outcomes for patients.

You, D. S., Cook, K. F., Domingue, B. W., Ziadni, M. S., Hah, J. M., Darnall, B. D., & Mackey, S. C. (2021). Customizing CAT Administration of the PROMIS Misuse of Prescription Pain Medication Item Bank for Patients with Chronic Pain. Pain medicine (Malden, Mass.), 22(7), 1669–1675. https://doi.org/10.1093/pm/pnab159

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Scherrer, K. H., Ziadni, M. S., Kong, J. T., Sturgeon, J. A., Salmasi, V., Hong, J., Cramer, E., Chen, A. L., Pacht, T., Olson, G., Darnall, B. D., Kao, M. C., & Mackey, S. (2021). Development and validation of the Collaborative Health Outcomes Information Registry body map. Pain reports, 6(1), e880. https://doi.org/10.1097/PR9.0000000000000880

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Ziadni, M. S., You, D. S., Sturgeon, J. A., Mackey, S. C., & Darnall, B. D. (2021). Perceived Injustice Mediates the Relationship Between Perceived Childhood Neglect and Current Function in Patients with Chronic Pain: A Preliminary Pilot Study. Journal of clinical psychology in medical settings, 28(2), 349–360. https://doi.org/10.1007/s10880-020-09722-8

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Azizoddin, D. R., Schreiber, K., Beck, M. R., Enzinger, A. C., Hruschak, V., Darnall, B. D., Edwards, R. R., Allsop, M. J., Tulsky, J. A., Boyer, E., & Mackey, S. (2021). Chronic pain severity, impact, and opioid use among patients with cancer: An analysis of biopsychosocial factors using the CHOIR learning health care system. Cancer, 127(17), 3254–3263. https://doi.org/10.1002/cncr.33645

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Gilam, G., Cramer, E. M., Weber, K. A., Ziadni, M. S., Kao, M. C., & Mackey, S. C. (2021). Classifying chronic pain using multidimensional pain-agnostic symptom assessments and clustering analysis. medRxiv. https://www.science.org/doi/10.1126/sciadv.abj0320

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Petrou, P. A., Leong, M. S., Mackey, S. C., & Salmasi, V. (2021). Stanford Pragmatic Effectiveness Comparison (SPEC) protocol: Comparing long-term effectiveness of high-frequency and burst spinal cord stimulation in real-world application. Contemp Clin Trials, 103, 106324. doi:10.1016/j.cct.2021.106324

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Wasan, A. D., O’Connell, B., DeSensi, R., Bernstein, C., Pickle, E., Zemaitis, M., Levy, O., Jeong, J. H., Cooper, G. F., & Douaihy, A. (2025). The comparative effectiveness of medicinal cannabis for chronic pain versus prescription medication treatment. Pain, 10.1097/j.pain.0000000000003506.

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Elwy, A. R., Taubenberger, S., Dodds, N., DeSensi, R., Gillman, A., Wasan, A., & Greco, C. M. (2023). Costs of Implementing Electronic Context Factor Assessments and Patient-reported Outcomes in Pain Clinic Settings. Medical care, 61(10), 699–707. https://doi.org/10.1097/MLR.0000000000001890

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